Designed by Henry Beaumont Herts, The Shubert Theatre was built at the same time as the adjoining Booth Theatre. The Shubert Theatre officially opened on Oct. 21, 1913 with Caesar and Cleopatra by George Bernard Shaw.

The theatre was named after Sam S. Shubert, and still houses the offices of the Shubert Organization on the top floor of the building. The Shubert Theatre has been designated a New York City landmark.