The Duke on 42nd Street is named after American heiress and philanthropist Doris Duke. The theatre opened in 2000, and is a 199-seat black box theatre.

Located next door to the Roundabout Theatre Company’s American Airlines Theatre between Seventh and Eighth Avenues, the Duke on 42nd Street offers companies the opportunity to perform on the famed 42nd Street. Since 2000,popular organizations have performed there, including The Playwright’s Realm, Red Bull Theater, Primary Stages, Theatre for a New Audience, and the National Theatre of Great Britain.